Effects of Radix Adenophorae and Cyclosporine A on an OVA-Induced Murine Model of Asthma by Suppressing to T Cells Activity, Eosinophilia, and Bronchial Hyperresponsiveness

Table 1

Effects of RAE on cytokines in CD4+ t cells isolated from Naive C57bl/6 Mice (NM: Normal C57BL/6 mice; CT: a-CD3/CD28+ CD4+ T cells; CsA: a-CD3/CD28+ CD4+ T cells + CsA; RAE 100: a-CD3/CD28+ CD4+ T cells + RAE (100 𝜇g/mL); RAE 50 : a-CD3/CD28+ CD4+ T cells + RAE (50 𝜇g/mL); RAE 10 : a-CD3/CD28+ CD4+ T cells + RAE (10 𝜇g/mL)).

	IFN-gamma (pg/mL)	IL-4 (pg/mL)	IL-5 (pg/mL)	IL-13 (pg/mL)
NM	1023.8 ± 39.3	693.8 ± 109.9	1.0 ± 0.2	15.2 ± 1.0
CT	1452.5 ± 62.4	4681 ± 303.5	54.5 ± 5.1	515.5 ± 18.7
CsA	809 ±  32.2^∗∗∗	537 ±  84.3^∗∗∗	3.9 ±  0.4^∗∗∗	15.4 ±  0.7^∗∗∗
RAE 100	2028.9 ±  192.9^∗	2859.5 ±  198.7^∗∗	21.7 ±  1.4^∗∗∗	316.2 ±  32.6^∗∗∗
RAE 50	1529.1 ± 159.9	3114.1 ±  76.2^∗∗	28.3 ±  2.7^∗∗	394.4 ±  21.7^∗∗
RAE 10	1335.4 ± 55.6	3597.2 ± 434.7	56.7 ± 4.6	496.5 ± 7.2