Research Article

Differential between Protein and mRNA Expression of CCR7 and SSTR5 Receptors in Crohn's Disease Patients

Table 1

Differential gene expression in (a) PBMCs of healthy donors and CD patients, (b) PBMCs of healthy donors and CD patients after LPS stimulation and (c) biopsies experiments. Results from each card were quantified in a relative comparative study, using an automatic baseline and threshold to record the cycle thresholds ( ) setting and the 18S rRNA gene expression as a reference for normalization ( ). Identification of genes differentially expressed in Crohn's patients versus control group was performed ( ) using standard statistical analysis methods as the Student's -test with the commonly accepted significance threshold of .
(a)

Assay IDGene SymbolGene NameT-TESTAverage Ct

Hs00265647_s1SSTR5 somatostatin receptor 50.0389.6
Hs00171054_m1CCR7 chemokine (C-C motif) receptor 70.16-6.56

(b)

Assai IDGene SymbolGene NameT-TESTAverage Ct

Hs00265647_s1SSTR5 somatostatin receptor 50.391.80

(c)

Assay IDGene SymbolGene NameT-TESTAverage

Hs00171054_m1CCR7 chemokine (C-C motif) receptor 70.033.36
Hs00265647_s1SSTR5 somatostatin receptor 50.331.31