Effects of Methotrexate on Plasma Cytokines and Cardiac Remodeling and Function in Postmyocarditis Rats

Table 2

Comparison of echocardiograph parameters of all three groups rats on day 60 (n = 10).

Groups	Control	EAM60	EAM-MTX
LVEDD (mm)	5.69 ± 0.29	6.46±0.28^∗	6.06±0.37^△
LVESD (mm)	2.24 ± 0.30	4.20±0.67^#	2.74± 0.41^*,▲
LVPWT (mm)	1.74 ± 0.17	1.54±0.20^∗	1.65 ± 0.21
IVST (mm)	1.76 ± 0.17	1.56±0.19^∗	1.68 ± 0.20
LVMI (mg/g)	1.52 ± 0.04	1.62 ± 0.17	1.60 ± 0.14
RWT	1.73 ± 0.24	2.12±0.32^∗	1.86 ± 0.35
FS (%)	62.31 ± 6.86	35.27±8.02^#	55.02 ± 4.16^*,▲
LVEF (%)	89.87 ± 4.40	62.73±10.11^#	84.77 ± 3.60^▲
SV (𝜇L)	162.38 ± 25.39	132.36±11.30^∗	156.02 ± 15.29^△

^∗𝑃<.05, ^#𝑃<.01 versus control group; ^△P < .05, ^▲P < .01 versus EAM60 group.