IL-4 Deficiency Decreases Mortality but Increases Severity of Arthritis in Experimental Group B
Streptococcus Infection
Figure 5
Chemokine production in joints . IL-4-deficient or wt mice infected with 1 107 GBS/mouse. Supernatants from joint homogenates were collected at the indicated times after infection and assayed for Mip-1 and MIP-2 by ELISA as detailed in materials and methods (see Section 2). Values are the mean SD of three separate experiments each consisting of 20 mice per experimental group. Three mice per group were sacrificed at each time point. Statistical differences between the experimental groups were marked with asterisk .
