Research Article

Pinellia ternata, Citrus reticulata, and Their Combinational Prescription Inhibit Eosinophil Infiltration and Airway Hyperresponsiveness by Suppressing CCR3+ and Th2 Cytokines Production in the Ovalbumin-Induced Asthma Model

Figure 1

(a), Schematic diagram of methacholine-induced AHR in the sensitization protocol. (b), PenH was measured in a Buxco box, as previously described in materials and methods. * , ** , *** asthma goup (control) versus PT, CR and their combinational prescription treated groups. (c), Effect of PT, CR and their combinational prescription on histology of lung tissue (H&E and M-Tstaining) in lung cells of OVA-induced murine model of asthma. H and E: hematoxylin-eosin stain, M-T: Masson trichrome stain, The results are expressed the mean S.E ( ). Statistically significant value compared with control group data by ANOVA (* , ** , *** ). N: Normal Balb/c mice, CT: Ovalbumin inhalation (control), OVA + CsA (10 mg/kg), OVA + PT(200, 400 mg/kg), OVA + CR(200, 400 mg/kg), OVA + (PT + CR) (200, 400 mg/kg).
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