Research Article

Pinellia ternata, Citrus reticulata, and Their Combinational Prescription Inhibit Eosinophil Infiltration and Airway Hyperresponsiveness by Suppressing CCR3+ and Th2 Cytokines Production in the Ovalbumin-Induced Asthma Model

Figure 2

Effects of PT, CR and their combinational prescription on total lung cells, total leucocytes, total lung weight, and total spleen cell. Mice were processed as described in materials and methods, and whole blood was harvested 24 hours after the last OVA challenge. Total inflammatory cell numbers in BALF, lung and spleen were counted, and cell classification was performed on a minimum of 200 cells to classify lymphocytes. The results are expressed the mean S.E ( ). Statistically significant value compared with control group data by ANOVA or unpaired Student’s t-test (* , ** , *** ). N: Normal Balb/c mice, CT: Ovalbumin inhalation (control group), CsA: OVA + CsA (10 mg/kg), OVA + PT(200, 400 mg/kg), OVA + CR(200, 400 mg/kg), OVA + (PT + CR) (200, 400 mg/kg).
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