Pinellia ternata, Citrus reticulata, and Their Combinational Prescription Inhibit Eosinophil Infiltration and Airway Hyperresponsiveness by Suppressing CCR3+ and Th2 Cytokines Production in the Ovalbumin-Induced Asthma Model

Figure 3

Quantification by means of FACS analysis of CD3-CCR3+ cell subtypes in BALF, spleen, lung, and PBMC. Absolute number of CD3-CCR3+ cell subtypes in BALF, spleen, lung and PBMC were counted (seen materials and methods). The results are expressed the mean ± S.E (𝑁=5). Statistically significant value compared with control group data by ANOVA or unpaired Student’s t-test (*𝑃<.05, ^**𝑃<.01, ^***𝑃<.001). N: Normal Balb/c mice, CT: Ovalbumin inhalation (control group), CsA: OVA + CsA (10 mg/kg), OVA + PT(200, 400 mg/kg), OVA + CR(200, 400 mg/kg), OVA + (PT + CR) (200, 400 mg/kg).

(a)

(b)

(c)

(d)

(e)