Mediators of Inflammation / 2009 / Article / Fig 3

Research Article

Influence of Melatonin on Cerebrovascular Proinflammatory Mediators Expression and Oxidative Stress Following Subarachnoid Hemorrhage in Rabbits

Figure 3

Changes of inflammatory mediators in the basilar arteries as determined by ELISA in control group ( ), SAH group ( ), SAH + vehicle group ( ), and SAH + melatonin group ( ). SAH could induce the significantly increased concentrations of IL-1 , TNF- and IL-6 in rabbit vascular tissue. In SAH + melatonin group, the arterial concentrations of IL-1 , TNF- and IL-6 were markedly downregulated as compared with that of SAH or SAH + vehicle group. * and ** versus Control group, ns versus SAH group, # and ## versus SAH + vehicle group.

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