Relationship between Mast Cells and the Colitis with Relapse
Induced by Trinitrobenzesulphonic Acid in Wistar Rats
Table 2
Damage score, changes in colonic weight, changes in body weight and incidence of adhesions and diarrhoea of colitic rats with relapse induced by TNBS.
Days of treatment
Damage score(a) (0–10)
Colonic weight(b) (mg/cm)
Body weight change (%)
Adhesions (%)
Diarrhoea (%)
0
0 (0–0)
67.2 ± 4.05
4.90 ± 0.50
0
0
2
7 (6–7.5)
129.0 ± 9.72
± 1.29
60
40
4
8 (6.5–9.5)
157.0 ± 17.35
± 0.52
80
100
6
7 (6–8)
196.8 ± 40.45
± 1.52
100
100
8
6 (5–7)
130.2 ± 9.38
15.98 ± 2.67
60
80
10
7 (3.5–8)
302.3 ± 63.78
24.02 ± 1.26
40
80
12
5 (1–5)
159.8 ± 16.09
23.78 ± 1.58
20
40
14
1 (1-1)
129.4 ± 6.01
26.48 ± 0.82
0
80
16
6 (6–6.5)
159.9 ± 18.21
10.52 ± 0.85
20
100
18
7 (6–8)
172.5 ± 17.37
14.68 ± 1.68
20
80
20
6 (5–6)
147.2 ± 9.59
24.95 ± 1.51
20
100
22
5.5 (5–6.5)
195.4 ± 17.77
29.12 ± 1.28
25
75
24
5 (5–6)
149.5 ± 15.01
30.02 ± 1.96
0
75
26
3 (2-2)
130.8 ± 4.97
35.85 ± 1.91
0
25
28
2 (2–3)
142.4 ± 3.76
50.02 ± 2.02
0
0
32
1 (1–4)
116.7 ± 6.89
51.58 ± 2.94
0
0
36
1 (0–1)
123.6 ± 5.89
56.44 ± 2.19
0
0
40
1 (0–1)
128.8 ± 3.23
62.85 ± 2.55
0
0
(a)Score data are expressed as median and interquartil interval.
(b)Body weight changes is expressed as percentage change from the start of the experiment ().
