Research Article

Relationship between Mast Cells and the Colitis with Relapse Induced by Trinitrobenzesulphonic Acid in Wistar Rats

Table 3

Comparison between noncolitic and TNBS-control groups on damage score, colonic weight, body weight changes and incidence of adhesions and diarrhoea.

Group ( ) and days of treatment Damage score(a) (0–10)Colonic weight(b) (mg/cm)Body weight change (%)Adhesion (%)Diarrhoea (%)

Noncolitic (saline) (day 8th)085.5 ± 2.7742.00 ± 3.9300
TNBS-control (day 8th)6 (5–7)*130.2 ± 9.38*29.15 ± 2.23*60*80*
Noncolitic (saline) (day 20th)088.5 ± 2.4241.70 ± 2.2400
TNBS-control (day 20th)6(5–6)*147.2 ± 9.59*34.18 ± 1.94*20*100*
Noncolitic (saline)(day 26th)0101.2 ± 6.2253.56 ± 2.3700
TNBS-control (day 26th)3(2-2)*130.8 ± 4.97*46.20 ± 1.45*50*50*
Noncolitic (saline) (day 28th)081.4 ± 1.9857.55 ± 2.1200
TNBS-control (day 28th)2(2–3)*142.4 ± 3.76*51.61 ± 1.19*00

(a)Score data are expressed as median and interquartil interval. (b)Colonic weight data are expressed as mean S.E.M. *Groups differ significantly from the noncolitic group .