Cardiotrophin-1 Induces Tumor Necrosis Factor <svg     style="vertical-align:-0.216pt;width:12.8625px;" id="M1" height="10.4375" version="1.1" viewBox="0 0 12.8625 10.4375" width="12.8625"  xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg">
	
		
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</svg> Synthesis in Human Peripheral Blood Mononuclear Cells

<table>CT-1 causes a concentration dependent increase of <svg height="11.375" id="M83" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 40.362499 11.375" width="40.362499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> activity measured by EMSA. Bands corresponding to <svg height="11.375" id="M84" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 40.362499 11.375" width="40.362499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> activity were quantified by densitometry and expressed in arbitrary units and normalized to unstimulated PBMC. <svg height="10.925" id="M85" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 36.237499 10.925" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>, data are expressed as mean<svg height="9.5625" id="M86" style="vertical-align:-0.3003pt" version="1.1" viewbox="0 0 21.4375 9.5625" width="21.4375" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>SEM. <svg height="17.825001" id="M87" style="vertical-align:-3.27605pt" version="1.1" viewbox="0 0 60.987499 17.825001" width="60.987499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared to unstimulated cells.</table>

Mediators of Inflammation

fig4

Figure 4

Figure 4: Cardiotrophin-1 Induces Tumor Necrosis Factor <svg     style="vertical-align:-0.216pt;width:12.8625px;" id="M1" height="10.4375" version="1.1" viewBox="0 0 12.8625 10.4375" width="12.8625"  xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg">
	
		
			<g transform="matrix(.022,-0,0,-.022,.062,10.1)"><path id="x1D6FC" d="M545 106q-67 -118 -134 -118q-24 0 -40 37.5t-30 129.5h-2q-47 -72 -103 -119.5t-108 -47.5q-47 0 -76 45.5t-29 119.5q0 113 85 204t174 91q47 0 70 -33.5t43 -119.5h3q32 47 80 140l55 13l10 -9q-47 -80 -138 -201q17 -99 27.5 -136t22.5 -37q23 0 69 61zM333 204
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</svg> Synthesis in Human Peripheral Blood Mononuclear Cells 

Mediators of Inflammation

Cardiotrophin-1 Induces Tumor Necrosis Factor Synthesis in Human Peripheral Blood Mononuclear Cells

Figure 4