Maintained Smoking Cessation for 6 Months Equilibrates the Percentage of Sputum CD𝟖⁺ Lymphocyte Cells with That of Nonsmokers

Table 2

Sputum differential cell counts and lymphocyte subpopulations.

		Smokers			Controls
	Total baseline	Successful quitters	Successful quitters	Successful quitters	(𝑛 = 10)
	(𝑛 = 51)	baseline	6 months	12 months
		(𝑛 = 16)	(𝑛 = 18)	(𝑛 = 9)
Weight, gr	1.2 (0.08–4.3)	1.4 (0.3–3.5)	0.89 (0.05–3.45)	1.08 (0.31–3.18)	1.41 (0.35–5.04)
TCC, ×10^6 cells	2.78 (0.06–13.2)	2.5 (0.1–11.2)	4.02 (0.59–11.8)	3.85 (0.47–19.6)	5.29 (1.16–7.00)
TCC/gr	2.27 (0.03–13.4)	1.6 (0.03–11.6)	4.78 (0.49–11.8)	2.86 (0.51–46.67)	2.18 (0.68–6.71)
Viability %	80.42 (50–98.6)	80.4 (50.6–96.9)	92.62 (50–99.37)	89.16 (70.37–98.53)	84.71 (67.01–98.79)
SQUAM	10 (0.01–49.9)	10.6 (0.01–43.7)	6.4 (0–20)	5 (0.49–39)	10.78 (2.31–48.5)
NEUTR %	55.6 (3.3–87.3)	48.8 (17.7–80)	55.3 (17–88)	61 (3.6–84.8)*	40.5 (3.6–94)
MACRO %	40.6 (12.3–94)	49.1 (20–80.3)	41.8 (11.2–82.2)	34.5 (14.5–57.3)	55 (5.4–94)
LYMPHO %	0.12 (0–6.2)	0.1 (0–6.2.7)	0.25 (0–1.5)	0.5 (0–1.6)	0.55 (0–4.1)
EOS %	0 (0–3.6)	0 (0–0)	0 (0–0)	0 (0–7)	0 (0–0.5)
CD4^+ %	59 (20–84)	58.5 (24–78.4)	54.7 (32.5–71)	40.2 (30.6–62)	53 (32–63)
CD8^+ %	13.9 (4–56)	13.6 (5–56)	24 (15–42)*	25.3 (12.5–46.6)*	22.3 (16–49) †
CD4^+/CD8^+ ratio	3.8 (0.4–16.2)	3.7 (0.4–12.9)	2.3 (1.1–4.7)*	1.9 (0.9–4.8)*	2.3 (0.9–3.2) †

TCC: total cell count, SQUAM: squamous cells, NEUTR: neutrophils, MACRO: macrophages, LYMPHO: lymphocytes, EOS: eosinophils.
Data are presented as median (range). Squamous cells are expressed as the percentage of all cells, differential cell counts are presented % of total sputum nonsquamous cells, lymphocyte subpopulations are presented % of total sputum lymphocytes.
^∗𝑃<.05 versus successful quitters at baseline, ^†𝑃<.05 between controls and successful quitters at baseline.