Leptin Inhibits the Proliferation of Vascular Smooth Muscle Cells Induced by Angiotensin II through Nitric Oxide-Dependent Mechanisms
Table 2
Metabolic characteristics of Zucker fa/fa rats.
Determination
Wistar rats (n = 14)
Zucker fa/fa rats (n = 10)
P value
Body weight (g)
283.6 ± 9.4
403.1 ± 4.9
.00001
Free fatty acids (mg/dL)
20.8 ± 1.7
15.7 ± 2.1
.081
Triglycerides (mg/dL)
105.3 ± 19.2
285.1 ± 16.6
.00001
Total cholesterol (mg/dL)
113.5 ± 6.4
131.4 ± 2.1
.05
Glucose (mg/dL)
133.4 ± 0.7
166.8 ± 1.1
.05
Insulin (ng/mL)
1.3 ± 0.3
10.8 ± 0.4
.00001
Leptin (ng/mL)
2.5 ± 0.1
49.8 ± 0.3
.00001
Values presented as the mean SEM. Differences between groups were analysed by Student’s t test. Bold values are statistically significant P values among groups.
