Clinical Study

Elevation of High-Mobility Group Protein Box-1 in Serum Correlates with Severity of Acute Intracerebral Hemorrhage

Figure 1

Serum level of HMGB1 increased significantly in patients with acute ICH. Data are presented as mean ± standard deviation. (a) ELISA assay of the changes of HMGB1 serum levels in patients. (b) A representative picture of Western blot assay showing the changes of HMGB1 serum levels in patients. GAPDH was chosen as the internal control. The changes of HMGB1 were expressed as the ratio of the optical density values of HMGB1 band to the optical density values of GAPDH band. **versus control; P<.01; ##versus good outcome group; P<.01.
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(a)
142458.fig.001b
(b)