Effect of Moderate-Intensity Exercise on Plasma C-Reactive Protein and Aortic Endothelial Function in Type 2 Diabetic Mice

Table 1

Body weights, plasma glucose CRP, and TNF-$\alpha$ levels in control or diabetic (db/db) mice that were either sedentary or exercised.

	Control sedentary			Control exercise			db/db Sedentary		db/db exercise
	6 wk	10 wk	14 wk	10 wk	14 wk	6 wk	10 wk	14 wk	10 wk	14 wk
Body weight (gm)	$20.7\pm 0.3$	$28.0\pm 0.3$	$31.9\pm 0.4$	$25.8\pm 0.4$	$28.3\pm 0.6{}^{*}$	$30.7\pm 0.4{}^{\#}$	$45.9\pm 0.7{}^{\#}$	$48.9\pm 1.2{}^{\#}$	$43.6\pm 1.0{}^{\#}$	$44.6\pm 1.3{}^{*\#}$
Fasting blood glucose (mg/dL)	$2.3\pm 0.1$	$5.0\pm 0.2$	$5.9\pm 0.5$	$5.3\pm 0.2$	$5.8\pm 0.2$	$5.7\pm 0.3{}^{\#}$	$31.5\pm 1.3{}^{\#}$	$54.7\pm 1.5{}^{\#}$	$30.3\pm 1.9{}^{\#}$	$44.6\pm 1.6{}^{*\#}\mathrm{\hspace{0.17em}\hspace{0.17em}}$
Plasma CRP (ng/mL)	$1.8\pm 0.3$	$2.6\pm 0.3$	$2.5\pm 0.4$	$3.8\pm 0.2{}^{*}$	$4.5\pm 0.3{}^{*}$	$3.3\pm 0.3{}^{\#}$	$4.1\pm 0.2{}^{\#}\mathrm{\hspace{0.17em}\hspace{0.17em}}$	$5.1\pm 0.3{}^{\#}\mathrm{\hspace{0.17em}\hspace{0.17em}}$	$3.8\pm 0.4{}^{\#}$	$3.6\pm 0.4{}^{*}$
PlasmaTNF-$\alpha$ (pg/mL)	N/A	N/A	$14.88\pm 0.35$	N/A	$14.30\pm 0.74$	N/A	N/A	$18.62\pm 2.11$	N/A	$20.53\pm 1.85$

${}^{*}P<.05$ compared to sedentary group at the same age.
${}^{\#}P<.05$ compared to control groups.
N/A: variable not measured