Disruption of Nrf2 Enhances the Upregulation of Nuclear Factor-kappaB Activity, Tumor Necrosis Factor-, and Matrix Metalloproteinase-9 after Spinal Cord Injury in Mice
Figure 6
MMP-9 expression by Western blot analysis in spinal cord homogenates from sham and injured Nrf2 (+/+) and Nrf2 (−/−) mice. (a) Representative X-ray film shows MMP-9 expression by Western blot analysis at 24 hours after SCI in sham and injured Nrf2 (+/+) and Nrf2 (−/−) mice. (b) The figure indicates that higher MMP-9 expression levels were found in Nrf2 (−/−) mice than in Nrf2 (+/+) mice at 24 hours after SCI. Bars represent mean S.E. (, each group). * versus sham control of the same genotype. # versus injured wild-type mice.