Ghrelin Protection against Lipopolysaccharide-Induced Gastric Mucosal Cell Apoptosis Involves Constitutive Nitric Oxide Synthase-Mediated Caspase-3 S-Nitrosylation

Figure 4

Effect of ghrelin on H. pylori LPS-induced expression of NOS-2 and cNOS activities in gastric mucosal cells. The cells, preincubated with the indicated concentrations of ghrelin, were treated with the LPS at 100 ng/mL and incubated for 16 h. Values represent the means ± SD of five experiments. ${}_{}{}^{*}P<.05$ compared with that of control. ${}_{}{}^{**}P<.05$ compared with that of LPS alone.