Nitric Oxide Synthase Enzymes in the Airways of Mice Exposed to Ovalbumin: NOS2 Expression Is NOS3 Dependent

Figure 11

Percentage PAS positive cells present in the airway epithelium from C57Bl/6, NOS1${}^{-/-}$, and NOS3${}^{-/-}$ genotype mice exposed to filtered air or OVA. Filtered air-exposed mice displayed an average of 0.45% PAS positive cells with no difference between the three groups. OVA-exposed NOS1${}^{-/-}$ mice had significantly fewer PAS positive-stained cells compared to the OVA-exposed C57Bl/6. Data are presented as mean values±SEM; ${}^{**}$ denotes $P<.01$ by ANOVA.