Effect of Feeding Status on Adjuvant Arthritis Severity, Cachexia, and Insulin Sensitivity in Male Lewis Rats

Figure 2

Plasma corticosterone (a), plasma CRP (b), IL-1$\beta$ mRNA expression (c), and CRP mRNA expression (d) in the liver of healthy control (CN, SHF, FR) and arthritic rats (AA-N, AA-SHF, AA-FR) measured on day 18 after cFA inoculation. Results of mRNA expressions are expressed in arbitrary units as the ratio of given mRNA to GAPDH. Significant differences between healthy controls on different dietary regime: ${}^{\times }P<.05\text{,}$${}^{\times \times \times }P<.001$. Statistical significances: control rats versus arthritic rats on the same dietary regime ${}^{*}P<.05\text{,}$${}^{**}P<.01\text{,}$${}^{***}P<.001$; AA-FR versus AA-N ${}^{\#}P<.05\text{,}$${}^{\#\#\#}P<.001$; AA-FR versus AA-SHF ${}^{++}P<.01$; AA-SHF versus AA-N ${}^{††}P<.01$. For abbreviations see Figure 1.

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