Review Article

Nonsteroidal Anti-Inflammatory Drugs for Wounds: Pain Relief or Excessive Scar Formation?

Figure 4

The keloid healing result. Several surface characteristics of keloid mark its difference from hypertrophic scar. However, there is only one difference in the initiating factors. There is no remolding phase in this aberrant wound healing process, and fibroblasts will not eventually turn into myofibroblasts. The abnormal scar is composed of disorganized type I and III collagens with thick irregular branched septa. On the cut surface, tongue-like advancing edges provoke its local advanced infiltrating nature.
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