Relevance of Serum Leptin and Leptin-Receptor Concentrations in Critically Ill Patients

Figure 1

Serum leptin and leptin-receptor concentrations in critically ill patients. (a) Serum leptin levels are not different in critically ill patients ($n=137$, median 5.5 ng/mL, range 0.4–49.6) as compared to healthy controls ($n=26$, median 6.6 ng/mL, range 0.7–38.6). (b) No significant differences are detected between ICU patients with sepsis ($n=95$, median 5.5 ng/mL, range 0.4–49.6) and nonseptic etiology ($n=42$, range 5.4 ng/mL, range 0.4–45.1) of critical illness. (c) Leptin-receptor serum concentrations do not differ between critically ill patients (median 31.5 ng/mL, range 5.7–126.9) and healthy controls (median 23.9 ng/mL, range 13.1–46.4). (d) No difference in serum leptin-receptor concentrations can be observed between patients with (median 31.8 ng/mL, range 5.7–126.9) or without sepsis (median 29.0 ng/mL, range 7.4–124.7) at admission to the ICU. Box plot are displayed, where the bold line indicates the median per group, the box represents 50% of the values, and horizontal lines show minimum and maximum values of the calculated nonoutlier values; asterixes and open circles indicate outlier values.

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