Mediators of Inflammation / 2010 / Article / Fig 2

Research Article

Effects of Sitagliptin Treatment on Dysmetabolism, Inflammation, and Oxidative Stress in an Animal Model of Type 2 Diabetes (ZDF Rat)

Figure 2

Serum inflammatory markers. Serum CRPhs (a), IL-1β (b), TNF-α (c) and Adiponectin (d) for the control (+/+) and diabetic (fa/fa) ZDF rats, in the initial and final times (6 weeks of vehicle or 10 mg/kg BW/day sitagliptin treatment). Comparisons between groups (n=8 each): a - ZDF (fa/fa) versus ZDF (+/+) and b - with sita versus without sita; P<.05, P<.01 and P<.001 for one, two or three letters, respectively. CRPhs, high-sensitive C-reactive protein; IL-1β, interleukin-1beta; TNF-α, Tumor necrosis factor-alpha.

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