Table of Contents Author Guidelines Submit a Manuscript
Mediators of Inflammation
Volume 2010, Article ID 627803, 7 pages
http://dx.doi.org/10.1155/2010/627803
Clinical Study

Temporomandibular Joint Bone Tissue Resorption in Patients with Early Rheumatoid Arthritis Can Be Predicted by Joint Crepitus and Plasma Glutamate Level

1Division of Clinical Oral Physiology, Department of Dental Medicine, Karolinska Institutet, P.O. Box 4064, 141 04 Huddinge, Sweden
2Division of Oral Radiology, Department of Dental Medicine, Karolinska Institutet, P.O. Box 4064, 141 04 Huddinge, Sweden
3Department of Rheumatology, Karolinska University Hospital, 141 86 Huddinge, Sweden

Received 15 October 2009; Revised 20 April 2010; Accepted 21 May 2010

Academic Editor: Oreste Gualillo

Copyright © 2010 Anna-Kari Hajati et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. Kopp and B. Rockler, “Relationship between clinical and radiographic findings in patients with mandibular pain or dysfunction,” Acta Radiologica—Series Diagnosis, vol. 20, no. 3, pp. 465–477, 1979. View at Google Scholar · View at Scopus
  2. S. Akerman, S. Kopp, M. Nilner, A. Petersson, and M. Rohlin, “Relationship between clinical and radiologic findings of the temporomandibular joint in rheumatoid arthritis,” Oral Surgery Oral Medicine and Oral Pathology, vol. 66, no. 6, pp. 639–643, 1988. View at Google Scholar · View at Scopus
  3. G. Peat, E. Thomas, R. Duncan et al., “Estimating the probability of radiographic osteoarthritis in the older patient with knee pain,” Arthritis Care and Research, vol. 57, no. 5, pp. 794–802, 2007. View at Publisher · View at Google Scholar · View at Scopus
  4. E. Jimenez-Boj, K. Redlich, B. Türk et al., “Interaction between synovial inflammatory tissue and bone marrow in rheumatoid arthritis,” Journal of Immunology, vol. 175, no. 4, pp. 2579–2588, 2005. View at Google Scholar · View at Scopus
  5. E. Jimenez-Boj, I. Nöbauer-Huhmann, B. Hanslik-Schnabel et al., “Bone erosions and bone marrow edema as defined by magnetic resonance imaging reflect true bone marrow inflammation in rheumatoid arthritis,” Arthritis and Rheumatism, vol. 56, no. 4, pp. 1118–1124, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. D. McGonagle, P. G. Conaghan, P. O'Connor et al., “The relationship between synovitis and bone changes in early untreated rheumatoid arthritis: a controlled magnetic resonance imaging study,” Arthritis and Rheumatism, vol. 42, no. 8, pp. 1706–1711, 1999. View at Publisher · View at Google Scholar · View at Scopus
  7. N. Dalbeth, T. Smith, S. Gray et al., “Cellular characterization of magnetic resonance imaging (MRI) bone edema in rheumatoid arthritis; implications for pathogenesis of erosive disease,” Annals of the Rheumatic Diseases, vol. 68, pp. 279–282, 2009. View at Google Scholar
  8. A.-K. Hajati, P. Alstergren, K. Näsström, J. Bratt, and S. Kopp, “Endogenous glutamate in association with inflammatory and hormonal factors modulates bone tissue resorption of the temporomandibular joint in patients with early rheumatoid arthritis,” Journal of Oral and Maxillofacial Surgery, vol. 67, no. 9, pp. 1895–1903, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. T. M. Skerry and A. F. Taylor, “Glutamate signalling in bone,” Current Pharmaceutical Design, vol. 7, no. 8, pp. 737–750, 2001. View at Publisher · View at Google Scholar · View at Scopus
  10. T. Takarada and Y. Yoneda, “Pharmacological topics of bone metabolism: glutamate as a signal mediator in bone,” Journal of Pharmacological Sciences, vol. 106, no. 4, pp. 536–541, 2008. View at Publisher · View at Google Scholar · View at Scopus
  11. L. E. Trang, P. Furst, A.-C. Odeback, and O. Lovgren, “Plasma amino acids in rheumatoid arthritis,” Scandinavian Journal of Rheumatology, vol. 14, no. 4, pp. 393–402, 1985. View at Google Scholar · View at Scopus
  12. S. Flood, R. Parri, A. Williams, V. Duance, and D. Mason, “Modulation of interleukin-6 and matrix metalloproteinase 2 expression in human fibroblast-like synoviocytes by functional ionotropic glutamate receptors,” Arthritis and Rheumatism, vol. 56, no. 8, pp. 2523–2534, 2007. View at Publisher · View at Google Scholar · View at Scopus
  13. A. Aliprandi, M. Longoni, L. Stanzani et al., “Increased plasma glutamate in stroke patients might be linked to altered platelet release and uptake,” Journal of Cerebral Blood Flow and Metabolism, vol. 25, no. 4, pp. 513–519, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. L. Tremolizzo, J. C. DiFrancesco, V. Rodriguez-Menendez et al., “Human platelets express the synaptic markers VGLUT1 and 2 and release glutamate following aggregation,” Neuroscience Letters, vol. 404, no. 3, pp. 262–265, 2006. View at Publisher · View at Google Scholar · View at Scopus
  15. H. Loppnow, R. Bil, S. Hirt et al., “Platelet-derived interleukin-1 induces cytokine production, but not proliferation of human vascular smooth muscle cells,” Blood, vol. 91, no. 1, pp. 134–141, 1998. View at Google Scholar · View at Scopus
  16. Ü. Voog, P. Alstergren, S. Eliasson, E. Leibur, R. Kallikorm, and S. Kopp, “Inflammatory mediators and radiographic changes in temporomandibular joints of patients with rheumatoid arthritis,” Acta Odontologica Scandinavica, vol. 61, no. 1, pp. 57–64, 2003. View at Google Scholar · View at Scopus
  17. Ü. Voog, P. Alstergren, S. Eliasson, E. Leibur, R. Kallikorm, and S. Kopp, “Progression of radiographic changes in the temporomandibular joints of patients with rheumatoid arthritis in relation to inflammatory markers and mediators in the blood,” Acta Odontologica Scandinavica, vol. 62, no. 1, pp. 7–13, 2004. View at Publisher · View at Google Scholar · View at Scopus
  18. G. K. M. Endresen, “Evidence for activation of platelets in the synovial fluid from patients with rheumatoid arthritis,” Rheumatology International, vol. 9, no. 1, pp. 19–24, 1989. View at Google Scholar · View at Scopus
  19. R. Battaglino, J. Fu, U. Späte et al., “Serotonin regulates osteoclast differentiation through its transporter,” Journal of Bone and Mineral Research, vol. 19, no. 9, pp. 1420–1431, 2004. View at Publisher · View at Google Scholar · View at Scopus
  20. M. M. Bliziotes, A. J. Eshleman, X.-W. Zhang, and K. M. Wiren, “Neurotransmitter action in osteoblasts: expression of a functional system for serotonin receptor activation and reuptake,” Bone, vol. 29, no. 5, pp. 477–486, 2001. View at Publisher · View at Google Scholar · View at Scopus
  21. M. F. Seidel, G. Ulrich-Merzenich, B. Fiebich, E. Candelario-Jalil, F. W. Koch, and H. Vetter, “Tropisetron inhibits serotonin-induced PGE2 release from macrophage-like synovial cells in serum-free tissue culture,” Scandinavian Journal of Rheumatology, Supplement, vol. 33, no. 119, p. 33, 2004. View at Publisher · View at Google Scholar · View at Scopus
  22. P. Alstergren and S. Kopp, “Pain and synovial fluid concentration of serotonin in arthritic temporomandibular joints,” Pain, vol. 72, no. 1-2, pp. 137–143, 1997. View at Publisher · View at Google Scholar · View at Scopus
  23. S. Kopp and P. Alstergren, “Blood serotonin and joint pain in seropositive versus seronegative rheumatoid arthritis,” Mediators of Inflammation, vol. 11, no. 4, pp. 211–217, 2002. View at Publisher · View at Google Scholar · View at Scopus
  24. K. W. Beagley and C. M. Gockel, “Regulation of innate and adaptive immunity by the female sex hormones oestradiol and progesterone,” FEMS Immunology and Medical Microbiology, vol. 38, no. 1, pp. 13–22, 2003. View at Publisher · View at Google Scholar · View at Scopus
  25. K. Ganesan, C. Balachandran, B. M. Manohar, and R. Puvanakrishnan, “Comparative studies on the interplay of testosterone, estrogen and progesterone in collagen induced arthritis in rats,” Bone, vol. 43, no. 4, pp. 758–765, 2008. View at Publisher · View at Google Scholar · View at Scopus
  26. M. Saika, D. Inoue, S. Kido, and T. Matsumoto, “17β-estradiol stimulates expression of osteoprotegerin by a mouse stromal cell line, ST-2, via estrogen receptor-α,” Endocrinology, vol. 142, no. 6, pp. 2205–2212, 2001. View at Publisher · View at Google Scholar · View at Scopus
  27. C. L. Clarke and R. L. Sutherland, “Progestin regulation of cellular proliferation,” Endocrine Reviews, vol. 11, no. 2, pp. 266–301, 1990. View at Google Scholar · View at Scopus
  28. B. L. Riggs, S. Khosla, and L. J. Melton III, “Sex steroids and the construction and conservation of the adult skeleton,” Endocrine Reviews, vol. 23, no. 3, pp. 279–302, 2002. View at Publisher · View at Google Scholar · View at Scopus
  29. F. C. Arnett, S. M. Edworthy, D. A. Bloch et al., “The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis,” Arthritis and Rheumatism, vol. 31, no. 3, pp. 315–324, 1988. View at Google Scholar · View at Scopus
  30. K. Buhlin, M. Hultin, O. Norderyd et al., “Risk factors for atherosclerosis in cases with severe periodontitis,” Journal of Clinical Periodontology, vol. 36, no. 7, pp. 541–549, 2009. View at Publisher · View at Google Scholar · View at Scopus
  31. P. Salven, A. Orpana, and H. Joensuu, “Leukocytes and platelets of patients with cancer contain high levels of vascular endothelial growth factor,” Clinical Cancer Research, vol. 5, no. 3, pp. 487–491, 1999. View at Google Scholar · View at Scopus
  32. A. Tegelberg and S. Kopp, “Subjective symptoms from the stomatognathic system in individuals with rheumatoid arthritis and osteoarthrosis,” Swedish Dental Journal, vol. 11, no. 1-2, pp. 11–22, 1987. View at Google Scholar · View at Scopus
  33. N. Graudal, “The natural history and prognosis of rheumatoid arthritis: association of radiographic outcome with process variables, joint motion and immune proteins,” Scandinavian Journal of Rheumatology. Supplement, no. 118, pp. 1–38, 2004. View at Google Scholar · View at Scopus
  34. C. Collet, C. Schiltz, V. Geoffroy, L. Maroteaux, J.-M. Launay, and M.-C. de Vernejoul, “The serotonin 5-HT2B receptor controls bone mass via osteoblast recruitment and proliferation,” FASEB Journal, vol. 22, no. 2, pp. 418–427, 2008. View at Publisher · View at Google Scholar · View at Scopus
  35. I. Westbroek, A. van der Plas, K. E. de Rooij, J. Klein-Nulend, and P. J. Nijweide, “Expression of serotonin receptors in bone,” Journal of Biological Chemistry, vol. 276, no. 31, pp. 28961–28968, 2001. View at Publisher · View at Google Scholar · View at Scopus
  36. M. Bliziotes, A. Eshleman, B. Burt-Pichat et al., “Serotonin transporter and receptor expression in osteocytic MLO-Y4 cells,” Bone, vol. 39, no. 6, pp. 1313–1321, 2006. View at Publisher · View at Google Scholar · View at Scopus