Activation of CD147 with Cyclophilin A Induces the Expression of IFITM1 through ERK and PI3K in THP-1 Cells

<table>GeneFishing analysis after CypA treatment in THP-1 cells revealed multiple differentially expressed genes. THP-1 cells were treated with or without 0.1 <math id="M34" xmlns="http://www.w3.org/1998/Math/MathML"><mrow><mi>μ</mi></mrow></math>M of CypA. Total cellular RNAs were isolated 20 hr after stimulation and differentially expressed gene (DEG) levels were analyzed by PCR using 20 different ACS random primer sets (GP1 through GP20). Results for GP1 through GP4 are shown in the figure. White boxes indicate the bands that were analyzed for identification through cloning and sequencing.</table>

Mediators of Inflammation

fig1

Figure 1

Figure 1: Activation of CD147 with Cyclophilin A Induces the Expression of IFITM1 through ERK and PI3K in THP-1 Cells 