The Effect of Chronic Candesartan Therapy on the Metabolic Profile and Renal Tissue Cytokine Levels in the Obese Zucker Rat

Figure 1

Plasma creatinine (a) and urinary albumin excretion (b) in candesartan-treated (CAN) or -untreated (c) lean and obese rats at the end of 14 weeks of treatment ($n=8$ per body type/treatment). Obese had significantly increased albumin excretion and higher plasma creatinine relative to lean groups; CANtreated groups were significantly different from control by 2-way ANOVA ($P<.05$). * indicates a significant difference ($P<.05$) from lean control mean and # from obese control mean by unpaired $t$-test.

(a)

(b)