Review Article

Scorpion Venom and the Inflammatory Response

Table 5

Mediators involved in envenomation.

ScorpionCytokines producedReferences

Androctonus australis hector
Experimental animal (rats)
IL-1β, IL-4, IL-6, IL-10, and TNF-α.[87]

Buthus martensi KarchNO and paw edema.[88]

Centruroides noxius
Experimental animal (mice)
IL-1β, IL-1α, IFN-γ IL-6, IL-10, and TNF-α.[76]

Leiurus quinquestriatus
Human and Experimental animal (rabbits)
IL-6, IL-8, NO, and TNF-α.[86, 89, 90]

Tityus serrulatus
Human and Experimental animal (rabbits)
IL-1β, IL-6, IL-8, IL-10, NO, TNF-α, IL-1α, IL-1β,IFN-γ, and GM-CSF.[8185, 91, 92]