Clinical Study

Inflammatory Molecules in Aqueous Humour and on Ocular Surface and Glaucoma Surgery Outcome

Table 2

Percentage of HLA-DR positive epithelial and CD80 positive cells (antigen-presenting cells) and mean fluorescence intensity (MFI) of ocular surface inflammatory molecules obtained by impression cytology at month 1 and 3 of follow-up in eyes with successful and failed surgery.

% of HLA-DR positive cells and their MFI median values (minimum-maximum)3 months after surgery6 months and 12 months after surgery
Success (n=  23)Failure (n=  7)PSuccess (n=  21)Failure (n=  9)P

% of HLA-DR positive epithelial cells at month 152 (11–97)83 (65–83).05858 (11–97)52 (32–83).960

MFI of HLA-DR on epithelial cells at month 114834 (2742–55237)16444 (3019–34050).90621369 (2742–55237)8094 (3019–16444).036

% of HLA-DR positive CD80 cells at 1 month64.5 (26–97)82 (70–96).12865 (26–97)68 (44–85).926

MFI of HLA-DR on CD80 positive cells at 1 month2686 (592–23661)2082 (1861–22194).8442728 (592–23661)2114 (1459–11540).514

% of HLA-DR positive epithelial cells at month 356 (7–93)56 (30–84).76255 (7–88)69 (30–93).402

MFI of HLA-DR on epithelial cells at month 35178 (533–20735)3450 (835–8747).4936150 (533-20735)2885 (1835–18634).082

% of HLA-DR positive CD80 cells at 3 month67 (48–99)67 (43–82).40166 (48-83)73 (43–99).920

MFI of HLA-DR on CD80 positive cells at 3 month4456 (1028–17943)6106 (1445–17808).5956050 (1028–17943)2755 (1340–17808).188

Mann-Whitney U test; significant at P  <.05.