Classification, Mechanisms of Action, and Therapeutic Applications of Inhibitory Oligonucleotides for Toll-Like Receptors (TLR) 7 and 9

Table 1

Oligonucleotides used in this study.

No.	Sequence	Class	Reference
2088	TCCTGGCGGGGAAGT	B/G	[58, 59]
2114	TCCTGGAGGGGAAGT	B/G	[58, 59]
4024	TCCTGGATGGGAAGT	B	[54, 55]
4084F	CCTGGATGGGAA	B	[62]
INH-1	CCTGGATGGGAATTCCCATCCAGG	R	[62]
INH-4	TTCCCATCCAGGCCTGGATGGGAA	R	[62]
INH-13	CTTACCGCTGCACCTGGATGGGAA	B	[62]
INH-18	CCTGGATGGGAACTTACCGCTGCA	B	[62]
Poly-G	GGGGGGGGGGGGGGGGGGGG	G	[47]
A151 (telomeric)	TTAGGGTTAGGGTTAGGGTTAGGG	G	[61]
GpG	TGACTGTGAAGGTTAGAGATGA	B	[56]
G-ODN	CTCCTATTGGGGGTTTCCTAT	B/G	[72]
IRS-869	TCCTGGAGGGGTTGT	B/G	[64]
IRS-661	TGCTTGCAAGCTTGCAAGCA	R/TLR7 specific	[71]
IRS-954	TGCTCCTGGAGGGGTTGT	B/TLR7/9 specific	[71]