Research Article

Lower Frequency of CD62Lhigh and Higher Frequency of TNFR2+ Tregs Are Associated with Inflammatory Conditions in Type 1 Diabetic Patients

Figure 3

Relationship between CD4+CD25high regulatory T-cells, their subpopulations frequencies, and HbA1c level in analyzed DM1 subjects. The level of HbA1c was measured in the blood of DM1 children and correlated with the percentage of peripheral blood regulatory T-cell subpopulations. The Spearman test was used to calculate the strength of correlation. (a) The correlation between CD4+CD25high frequency and HbA1c level in DM1 subjects ( ); (b) the correlation between CD4+CD25highCD62Lhigh frequency and HbA1c level in DM1 subjects ( ); (c) the correlation between CD4+CD25highTNFR2+ frequency and HbA1c level in DM1 subjects ( ). *The percentage of cells among peripheral blood lymphocytes, **the percentage of cells among CD4+CD25high lymphocytes.
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(a)
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(b)
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(c)