Lower Frequency of CD62L^high and Higher Frequency of TNFR2⁺ Tregs Are Associated with Inflammatory Conditions in Type 1 Diabetic Patients

Table 2

The percentage and number of CD4⁺CD25^high, CD4⁺CD25^highCD62L^high, and CD4⁺CD25^highTNFR2⁺ T cells.

	Children with DM1	Control group	𝑃
	(𝑛=35)	(𝑛=20)
The percentage of CD4^+CD25^high cells (%)*	1.56 (0.4/4.6)	3.30 (2.5/4.9)	.00026
The absolute number of CD4^+CD25^high (cells/mm^3)	0.37 (0.03/4.17)	1.13 (0.55/2.21)	.00084
The percentage of CD4^+CD25^high CD62L^highcells (%)**	54.3 (20.0/79.2)	90.2 (76.4/94.3)	.00000
The absolute number of CD4^+CD25^high CD62L^high cells (cells/mm^3)	0.014 (0.02/2.76)	1.01 (0.48/2.08)	.000012
The percentage of CD4^+CD25^highTNFR2^+cells (%)**	96.9 (85.7/99.8)	34.95 (21.6/46.0)	.0000
The absolute number of CD4^+CD25^highTNFR2^+cells (cells/mm^3)	0.27 (0.03/4.158)	0.4 (0.11/1.08)	.26

Results are shown as median and 10th percentile/90th percentile. All the differences were calculated by the 𝑈-Mann Whitney test.
*The percentage of cells among peripheral blood lymphocytes.
**The percentage of cells among CD4⁺CD25^high lymphocytes.