Clinical Study
Angiogenesis-Related Cytokines, RANKL, and Osteoprotegerin in Multiple Myeloma Patients in relation to Clinical Features and Response to Treatment
Table 3
Mean ± SD values of the measured parameters in the group of MM patients according to the skeletal involvement.
| | Bone involvement | Mean ± SD | |
| | OPG (pmol/L) | Low Score (Grade 0-1) | | NS | | High Score (Grade 2-3) | | | | RANKL pmol/L | Low Score (Grade 0-1) | | < 0.001 | | High Score (Grade 2-3) | | | | RANKL/OPG | Low Score (Grade 0-1) | | < 0.001 | | High Score (Grade 2-3) | | | | HGF (pg/mL) | Low Score (Grade 0-1) | | < 0.004 | | High Score (Grade 2-3) | | | | LDH (IU/L) | Low Score (Grade 0-1) | | 0.05 | | High Score (Grade 2-3) | | | | VEGF (pg/mL) | Low Score (Grade 0-1) | | < 0.001 | | High Score (Grade 2-3) | | | | B2M (mg/dL) | Low Score (Grade 0-1) | | < 0.04 | | High Score (Grade 2-3) | | | | CRP (mg/L) | Low Score (Grade 0-1) | | NS | | High Score (Grade 2-3) | | | | IL-6 (pg/mL) | Low Score (Grade 0-1) | | < 0.001 | | High Score (Grade 2-3) | | |
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