Inhibition of Osteoclast Generation: A Novel Function of the Bone Morphogenetic Protein 7/Osteogenic Protein 1
Figure 1
Typical morphological appearance of osteoclasts: after 10 to 14 d in culture (data from day 12 are shown) giant cells were seen ((a); ×400), which expressed TRAP (b), cathepsin K (c) (shown in red, thick arrow), had multiple nuclei (blue) (c), (d), and the typical ring-like distribution of actin (green). Images as shown in (d) were used for quantification.
