MCP-1-Induced Histamine Release from Mast Cells Is Associated with Development of Interstitial Cystitis/Bladder Pain Syndrome in Rat Models

Figure 1

MCP-1 immunodetection. LPS-treated rats showed increased expression of MCP-1 in bladder tissues. (a) and (c) Control group (𝑛=3); (b) and (d) Model group (𝑛=6). ((a) and (b): ×40; (c) and (d): ×400). ELISA results indicate that MCP-1 levels in bladder tissue (e) and urine (f) from the Model group were elevated compared to levels observed in the Control group (𝑃<0.05).

(a)

(b)

(c)

(d)

(e)

(f)