MCP-1-Induced Histamine Release from Mast Cells Is Associated with Development of Interstitial Cystitis/Bladder Pain Syndrome in Rat Models
Figure 3
LPS-induced degranulation of mast cells. (a) Control group (); (b) Model group (). The mast cells with or without degranulation are indicated with red or blue arrows, respectively. Double-labeled immunofluorescence microscopy showing MCP-1 interactions with mast cells in bladder tissues. (c) Control group (); (d) Model group (). Nuclei are colored blue by DAPI; green fluorescence indicates MCP-1 protein immunostaining; red fluorescence indicates MC immunostaining. Scale bars in the immunofluorescence images represent 20 μm.
