Research Article

Disruption of the ECM33 Gene in Candida albicans Prevents Biofilm Formation, Engineered Human Oral Mucosa Tissue Damage and Gingival Cell Necrosis/Apoptosis

Table 1

Candida strains used in this study.

StrainRelevant characteristicsReference

CAF2-parental strainURA3ura3::imm43 [16]
RML1-heterozygous ecm33 mutantCaECM33/ΔCaecm33:: hisG-CaURA3-hisG [17]
RML2-homozygous double ecm33 mutant Caecm33Δ:: hisG/Caecm33Δ:: hisG-CaURA3-hisG [17]
RML3-heterozygous revertantCaecm33Δ:: hisG/CaECM33-clz-URA3-clz-hisG [17]
RML4-homozygous revertantCaECM33-clz-hisG/CaECM33-clz-URA3-clz-hisG[17]