Clinical Study

Inflammatory Mediators in Induced Sputum and Airway Hyperresponsiveness in Cough Variant Asthma during Long-Term Inhaled Corticosteroid Treatment

Table 1

Clinical characteristics of the three studied groups.

CVA group ( )Asthma group ( )Control group ( )

Sex (M : F)28 (13 : 15)23 (10 : 13)22 (12 : 10)
Age (years)42.96 ± 14.2340.73 ± 11.4138.76 ± 13.18
Total IgE (IU·mL-1)657.85 (24.00 ~ 2342.00)a593.74 (37.40 ~ 2592.00)a65.46 (17.34 ~ 153.00)
FEV1% predicted93.76 ± 12.7290.24 ± 15.11102.12 ± 14.49
FEV1/FVC82.67 ± 4.7684.13 ± 6.9289.21 ± 4.7
Leukocyte (109/L)6.65 ± 1.787.06 ± 1.916.71 ± 1.72
Neutrophil (%)56.85 ± 9.5260.72 ± 9.4757.39 ± 7.20
Eosinophil (%)7.28 ± 2.46a6.86 ± 2.58a3.08 ± 1.91
Basophil (%)0.092 ± 0.0760.074 ± 0.0620.088 ± 0.049
Monocytes (%)6.29 ± 1.056.47 ± 1.906.51 ± 1.35
Lymphocytes (%)29.55 ± 8.8333.16 ± 14.2727.86 ± 15.23
Atopy12/16 a10/13a0/22

compared with controls.