Clinical Study

Value of C-Reactive Protein as a Risk Factor for Acute Coronary Syndrome: A Comparison with Apolipoprotein Concentrations and Lipid Profile

Table 5

The risk of the acute coronary syndrome for primary and secondary variables.

ParameterCrude odds ratioAdjusted odds ratio
Model 0* OR
P value for the model
Model 1 OR (95% CI)
P value for the model
Model 2 OR (95% CI)
P value for the model
Model 3 OR (95% CI)
P value for the model

TC 1.10 (0.95–1.29)1.08 (0.96–1.22)1.11 (0.98–1.26)1.59 (0.66–3.83)
nsnsnsns
LDL-C 0.90 (0.78–1.04)0.87 (0.78–0.98)0.85 (0.75–0.95)0.59 (0.24–1.45)
ns0.0240.007ns
HDL-C0.88 (0.75–1.04)0.95 (0.82–1.1)0.92 (0.80–1.07)0.42 (0.15–1.16)
nsnsnsns
TG 0.99 (0.95–1.02)1.01 (0.97–1.04)0.99 (0.96–1.03)0.80 (0.63–1.01)
nsnsnsns
apoA-I0.99 (0.96–1.02)0.96 (0.92–1.01)0.96 (0.92–1.01)1.02 (0.87–1.2)
nsnsnsns
apoB 0.99 (0.94–1.05)0.99 (0.92–1.06)0.99 (0.92–1.07)0.97 (0.75–1.26)
nsnsnsns
hsCRP
1.60 (1.31–1.95)1.56 (1.21–2.01)1.64 (1.26–2.13)1.90 (1.34–2.89)
0.00010.0010.00010.001
nonHDL-C
1.01 (0.97–1.04)1.04 (0.99–1.09)1.05 (0.99–1.1)1.32 (0.85–2.04)
nsnsnsns
TC : HDL-C0.76 (0.8–6.81)6.42 (0.32–125.6)6.01 (0.25–145.3)0.00 (0.27–104797)
nsnsnsns
TG : HDL-C0.92 (0.37–2.3)0.36 (0.13–0.99)0.38 (0.13–1.08)976 (0.17–5713045)
ns0.05nsns
LDL-C : HDL-C2.75 (0.49–15.37)0.92 (0.11–7.83)0.72 (0.73–7.03)12.1 (0.00–1.878E1)
nsnsnsns
apoB : apoA-I0.50 (0.001–402.2)1.09 (0.01–10916)0.39 (0.000–1853)18.2 (0.000–4.117E1)
nsnsnsns

*Model 0 unadjusted: = 139.2; df = 12; P < 0.001; log-likelihood = 268.0; Cox and Snell = 0.35; Nagelkerke = 0.49.
Model 1 adjusted for age: = 251.8; df = 13; P = 0.001; log-likelihood = 155.4; Cox and Snell = 0.54; Nagelkerke = 0.75.
Model 2 adjusted for age and sex: = 259.6; df = 14; P < 0.001; log-likelihood = 147.6; Cox and Snell = 0.55; Nagelkerke = 0.77.
Model 3 adjusted for age, sex, and smoking status: = 233.4; df = 15; P < 0.001; log-likelihood = 50.9; Cox and Snell = 0.64; Nagelkerke = 0.90.
apoA-I: apolipoprotein A-I; apoB: apolipoprotein B; apoB : apoA-I: apolipoprotein B to apolipoprotein A-I ratio; CI: confidence interval; HDL-C: high-density lipoprotein cholesterol; hsCRP: high-sensitivity C-reactive protein; LDL-C: low-density lipoprotein cholesterol; LDL-C : HDL-C: low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio; non-HDL-C: nonhigh-density lipoprotein cholesterol; ns: not significant; OR: odds ratio; TC: total cholesterol; TC : HDL-C: total cholesterol to high-density lipoprotein cholesterol ratio; TG: triglycerides; TG : HDL-C: triglycerides to high-density lipoprotein cholesterol ratio.