Mediators of Inflammation / 2012 / Article / Tab 1

Research Article

Low Dose Theophylline Showed an Inhibitory Effect on the Production of IL-6 and IL-8 in Primary Lung Fibroblast from Patients with COPD

Table 1

Clinical and demographic features of the subjects.

COPDControl 𝑃 value

Gender (M/F)5/55/3NS
Age (yrs) 6 5 . 3 ± 9 . 8 6 9 . 5 ± 3 . 1 NS
Smoking history (pack-yrs) 4 3 . 0 ± 1 7 . 7 3 0 . 0 ± 1 0 . 0 NS
FEV1 (L) 1 . 3 5 ± 0 . 2 6 2 . 2 0 ± 0 . 3 3 <0.001
FEV1% pred 6 8 . 7 ± 1 8 . 7 9 0 . 2 ± 5 . 5 0.0128
FVC (L) 2 . 7 5 ± 0 . 7 6 2 . 9 7 ± 0 . 4 5 NS
FVC% pred 8 6 . 2 ± 2 0 . 5 8 9 . 0 ± 1 0 . 2 NS
FEV1/FVC% 5 7 . 4 ± 8 . 8 7 9 . 3 ± 9 . 4 <0.001

Data are presented as mean ± SD. COPD: chronic obstructive pulmonary disease; M: male; F: female; FEV1: forced expiratory volume in one second; % pred: % predicted; FVC: forced vital capacity; NS: nonsignificant. Subjects having an FEV1/FVC < 70%. Subjects having an FEV1/FVC ≥ 70%.

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