Mediators of Inflammation

Research Article

Anti-Inflammatory Effects of Concentrated Ethanol Extracts of Edelweiss (Leontopodium alpinum Cass.) Callus Cultures towards Human Keratinocytes and Endothelial Cells

Table 1

Quantification of phenolic extracts of aerial parts of Edelweiss plant, Leontopodium alpinum callus cultures, and concentrated extract enriched in leontopodic acids (ECC55).
PhenolicsCapitula of Edelweiss*(%) [12]Leontopodium alpinum callus cultures (%)ECC55 (%)
Chlorogenic acid0.51.224
3,5-Dicaffeoylquinic acid1.00.821
Leontopodic acid B0.51.014
Leontopodic acid3.02.241
LuteolineTraces— 
ApigenineTraces— 
IsoquercetinTraces— 
Luteolin-7,4′-di-O-β-D-glucoside0.1— 
Luteolin-4′-O-β-D-glucoside0.3— 
Luteolin-7-O-β-D-glucosideTraces— 
Luteolin-3′-O-β-D-glucoside0.1— 
Apigenin-7-O-β-D-glucosideTraces— 
Chrysoeriol-7-O-β-D-glucosideTraces— 
6-Hydroxy-luteolin-7-O-β-D-glucoside — 
Pentahydroxyflavone Traces 1.5 
* Content of chlorogenic acid, 3,5-dicaffeoylquinic acid, leontopodic acid B, and leontopodic acid was different in the stems, stem leaves, capitula, in-florescences leaves, and leaves of the basal rosette [12].