Elevated Circulating Interleukin-27 in Patients with Coronary Artery Disease Is Associated with Dendritic Cells, Oxidized Low-Density Lipoprotein, and Severity of Coronary Artery Stenosis
Table 1
Clinical characteristics of patient cohort.
Control
SAP
UAP
AMI
Age (years)
63.793 ± 8.381
60.767 ± 10.553
62.232 ± 10.322
61.960 ± 9.583
0.700
Male gender, (%)
21 (72.414)
21 (70)
39 (69.643)
32 (80)
0.865
Risk factors, (%)
Hypertension
9 (31.034)
9 (30)
20 (35.714)
11 (22)
0.493
Current smoking
12 (41.379)
16 (53.333)
25 (44.643)
20 (40)
0.691
Diabetes mellitus
5 (17.241)
7 (23.333)
12 (21.429)
13 (26)
0.836
Medication, (%)
Ca-antagonist
4 (13.793)
6 (20)
10 (17.857)
7 (14)
0.868
Aspirin
7 (24.138)
10 (30.303)
18 (32.143)
20 (40)
0.547
β-blockers
5 (17.241)
4 (13.333)
8 (14.286)
6 (12)
0.933
Other antiplatelet agents
2 (6.897)
3 (10)
7 (12.5)
12 (24)
0.132
TC (mmol/L)
5.188 ± 1.271
4.807 ± 1.196
4.875 ± 1.229
4.885 ± 1.166
0.618
LDL-C (mmol/L)
2.387 ± 0.669
2.918 ± 1.000a
2.798 ± 0.682a
2.916 ± 0.871a
0.029
TG (mmol/L)
1.292 ± 0.636
1.311 ± 0.470
1.338 ± 0.528
1.398 ± 0.544
0.830
Leukocytes (G/L)
7.060 ± 1.491
7.664 ± 2.031
7.193 ± 1.877
7.138 ± 2.042
0.587
Creatinine (μmol/L)
89.931 ± 20.664
98.100 ± 19.744
95.750 ± 16.282
94.620 ± 18.951
0.380
Uric acid (μmol/L)
283.830 ± 95.354
324.730 ± 111.372
312.930 ± 108.287
334.500 ± 75.393a
0.161
cTnI (μg/L)
0.012 ± 0.004
0.017 ± 0.010a
0.054 ± 0.112a
15.572 ± 16.487a, b, c
<0.001
Values are expressed as percentages or mean ± SD. versus control subjects; versus stable angina pectoris patients; versus unstable angina pectoris patients. SAP: stable angina pectoris; UAP: unstable angina pectoris; AMI: acute myocardial infarction; TC: total cholesterol; LDL-C: low-density lipoprotein cholesterol; TG: triglycerides; cTnI: cardiac troponin I.
