The Role of Src Kinase in Macrophage-Mediated Inflammatory Responses

Table 4

Plant extracts inhibiting Src activation in macrophages.

Plant	Target Src pathway	Reference
Archidendron clypearia	Src/NF-κB-targeted inhibition of LPS-induced macrophage activation and dextran sodium sulfate-induced colitis	[97]
Polygonum hydropiper	Suppression of Src/Syk/NF-κB and IRAK/AP-1/CREB pathways and dextran sodium sulfate-induced colitis	[98]
Cinnamomum cassia	Suppression of Src/Syk-mediated NF-κB activation and antigastritis	[99]
Phaseolus angularis beans	NO and PGE2 production mediated by the suppression of NF-κB and AP-1 activation signaling cascade and antigastritis	[100]
Sorbus commixta	Suppression of the inflammatory signaling cascade composed of Src, Syk, and NF-κB.	[101]
Sanguisorba officinalis	NO and PGE2 production mediated by the suppression of NF-κB and AP-1 activation signaling cascade	[102]