Anti-Inflammatory Properties of Sirtuin 6 in Human Umbilical Vein Endothelial Cells
Figure 5
Effect of SIRT6 knockdown on ECM remodelling enzymes. HUVECs were transfected with 50 nM SIRT6 or NS siRNA for 72 h followed by 10 g/mL LPS for 24 h (). MMP-2, MMP-9 and PAI-1 mRNA expression was quantified by qRT-PCR. Each bar represents the mean SEM. versus NS siRNA + LPS.
