Table of Contents Author Guidelines Submit a Manuscript
Mediators of Inflammation
Volume 2012, Article ID 608249, 5 pages
http://dx.doi.org/10.1155/2012/608249
Research Article

Usefulness of Faecal Calprotectin Measurement in Children with Various Types of Inflammatory Bowel Disease

1Department of Paediatrics, Medical University of Silesia, Medykow 16, 40-752 Katowice, Poland
2Department of Pathomorphology, Medical University of Silesia, 40-752 Katowice, Poland

Received 16 January 2012; Revised 29 February 2012; Accepted 2 March 2012

Academic Editor: Antonio Macciò

Copyright © 2012 Marzena Komraus et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. F. Costa, M. G. Mumolo, L. Ceccarelli et al., “Calprotectin is a stronger predictive marker of relapse in ulcerative colitis than in Crohn's disease,” Gut, vol. 54, no. 3, pp. 364–368, 2005. View at Publisher · View at Google Scholar · View at Scopus
  2. A. G. Røseth, E. Aadland, and K. Grzyb, “Normalization of faecal calprotectin: a predictor of mucosal healing in patients with inflammatory bowel disease,” Scandinavian Journal of Gastroenterology, vol. 39, no. 10, pp. 1017–1020, 2004. View at Google Scholar
  3. A. Szarszewski, M. Korzon, J. Kurlenda, A. Liberek, B. Kamińska, M. Bogotko-Szarszewska et al., “Faecal calprotectin: a new acute inflammatory reactant in the diagnosis of Childhood Inflammatory Bowel Disease-own experience,” Medical Science Monitor, vol. 9, 4, pp. 11–13, 2003. View at Google Scholar
  4. N. Kobelska-Dubiel, I. Ignaś, H. Krauss, W. Cichy, and M. Kobelski, “Kalprotektyna w kale jako marker zapalny w nieswoistych zapaleniach jelit u dzieci,” Pediatria Współczesna Gastroenterologia, Hepatologia i Żywienie Dziecka, vol. 9, no. 3, pp. 172–175, 2007. View at Google Scholar
  5. R. B. Canani, L. T. De Horatio, G. Terrin et al., “Combined use of noninvasive tests is useful in the initial diagnostic approach to a child with suspected inflammatory bowel disease,” Journal of Pediatric Gastroenterology and Nutrition, vol. 42, no. 1, pp. 9–15, 2006. View at Publisher · View at Google Scholar · View at Scopus
  6. M. Joishy, I. Davies, M. Ahmed et al., “Fecal calprotectin and lactoferrin as noninvasive markers of pediatric inflammatory bowel disease,” Journal of Pediatric Gastroenterology and Nutrition, vol. 48, no. 1, pp. 48–54, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. U. L. Fagerberg, L. Lööf, U. Myrdal, L. O. Hansson, and Y. Finkel, “Colorectal inflammation is well predicted by fecal calprotectin in children with gastrointestinal symptoms,” Journal of Pediatric Gastroenterology and Nutrition, vol. 40, no. 4, pp. 450–455, 2005. View at Publisher · View at Google Scholar · View at Scopus
  8. A. Carroccio, G. Iacono, M. Cottone et al., “Diagnostic accuracy of fecal calprotectin assay in distinguishing organic causes of chronic diarrhea from irritable bowel syndrome: a prospective study in adults and children,” Clinical Chemistry, vol. 49, no. 6, pp. 861–867, 2003. View at Publisher · View at Google Scholar · View at Scopus
  9. J. A. Tibble and I. Bjarnason, “Non-invasive investigation of inflammatory bowel disease,” World Journal of Gastroenterology, vol. 7, no. 4, pp. 460–465, 2001. View at Google Scholar · View at Scopus
  10. S. K. Bunn, W. M. Bisset, M. J. Main, E. S. Gray, S. Olson, and B. E. Golden, “Fecal calprotectin: validation as a noninvasive measure of bowel inflammation in childhood inflammatory bowel disease,” Journal of Pediatric Gastroenterology and Nutrition, vol. 33, no. 1, pp. 14–22, 2001. View at Google Scholar
  11. M. R. Konikoff and L. A. Denson, “Role of fecal calprotectin as a biomarker of intestinal inflammation in inflammatory bowel disease,” Inflammatory Bowel Diseases, vol. 12, no. 6, pp. 524–534, 2006. View at Publisher · View at Google Scholar · View at Scopus
  12. S. T. Leach and A. S. Day, “S100 proteins in the pathogenesis and diagnosis of inflammatory bowel disease,” Expert Review of Clinical Immunology, vol. 2, no. 3, pp. 471–480, 2006. View at Publisher · View at Google Scholar · View at Scopus
  13. K. Geboes and G. De Hertogh, “Indeterminate colitis,” Inflammatory Bowel Diseases, vol. 9, no. 5, pp. 324–331, 2003. View at Publisher · View at Google Scholar · View at Scopus
  14. A. Bremner, S. Roked, R. Robinson, I. Phillips, and M. Beattie, “Faecal calprotectin in children with chronic gastrointestinal symptoms,” Acta Paediatrica, vol. 94, no. 12, pp. 1855–1858, 2005. View at Publisher · View at Google Scholar · View at Scopus
  15. U. L. Fagerberg, L. Lööf, J. Lindholm, L. O. Hansson, and Y. Finkel, “Fecal calprotectin: a quantitative marker of colonic inflammation in children with inflammatory bowel disease,” Journal of Pediatric Gastroenterology and Nutrition, vol. 45, no. 4, pp. 414–420, 2007. View at Publisher · View at Google Scholar · View at Scopus
  16. A. G. Røseth, E. Aadland, J. Jahnsen, and N. Raknerud, “Assessment of disease activity in ulcerative colitis by faecal calprotectin, a novel granulocyte marker protein,” Digestion, vol. 58, no. 2, pp. 176–180, 1997. View at Google Scholar
  17. T. Heliö, L. Halme, M. Lappalainen, H. Fodstad, P. Paavola-Sakki, U. Turunen et al., “CARD15/NOD2 gene variants are associated with familially occurring and complicated forms of Crohn’s disease,” Gut, vol. 52, no. 4, pp. 558–562, 2003. View at Google Scholar
  18. U. Grzybowska-Chlebowczyk, H. Woś, A. Sieroń, M. Kajor, S. Więcek, H. Koryciak-Komarska et al., “Objawy pozajelitowe i powikŁania u dzieci z nieswoistymi zapaleniami jelit w zaleźności od mutacji genu CARD15,” Medycyna Wieku Rozwojowego, vol. 12, no. 3, pp. 754–760, 2008. View at Google Scholar