Research Article

Changes in the Monocytic Subsets CD14dimCD16+ and CD14++CD16 in Chronic Systolic Heart Failure Patients

Table 4

Association between serum cytokines and HF.

CytokineCutoff valueControl N, (%)Range (pg/mL)HF patients N, (%)Range
(pg/mL)
O.R.a95% CIP valueAUC
(95% CI)

TNF (pg/mL)<0
≥1
20, 87%
3, 13%
0–2.730, 61%
19, 39%
0–2764.1751.045–16.680.043*0.720
(0.597–0.843)
IL-1 (pg/mL)<9.8
≥9.8
16, 70%
7, 30%
0–5121, 41%
30, 59%
0–3623.3901.133–10.140.029*0.692
(0.573–0.811)
IL-10 (pg/mL)<10
≥10
16, 70%
7, 30%
0–18.920, 41%
29, 59%
0–2363.7511.237–11.380.020*0.733
(0.609–0.857)
TGF (pg/mL)<100
≥100
10, 43%
13, 56%
28–28027, 53%
24, 47%
27–6190.6940.252–1.910.479ns0.657
(0.527–0.788)
IL-13 (pg/mL)<9
≥9
20, 87%
3, 13%
0–3417, 33%
34, 64%
0–37114.3933.48–59.5<0.001***0.797
(0.685–0.908)

aOdds ratio calculated by the logistic regression models is adjusted for age and gender.