Alterations in Monocyte CD16 in Association with Diabetes Complications
Table 2
Plasma levels of cytokines and chemokines in control and diabetic subjects.
(pg/mL)
Control
Diabetic
Diabetic
()
()
D−Comps ()
D+Comps ()
Cytokines
IL-6#
3.2 (2.1–5.3)
3.8 (2.7–4.8)
4.5 (3.2–7.1)
3.6 (2.6–4.2)
IL-8#
3.1 (1.8–4.4)
4.5 (3.3–5.5)*
5.1 (3.7–6.4)
3.7 (2.9–4.6) †
TNF-α #
10.4 (7.6–20.1)
12.2 (8.5–19.8)
12.8 (10.4–23.8)
10.0 (5.5–12.8) †
IFN-γ #
61.6 (46.6–85.5)
56.8 (49.3–76.9)
68.4 (53.5–113.4)
50.3 (45.6–59.7) †
IL-10#
0.03 (0.00–0.43)
0.52 (0.07–0.94)*
0.46 (0.00–0.82)
0.83 (0.20–1.08)
Chemokines
IP-10
MCP-1#
14.7 (12.0–22.1)
21.7 (15.0–35.7)*
19.2 (14.8–35.1)
23.6 (15.7–43.4)
MIP-1
†
Results are expressed as mean ± SD, except (#) shown as median with interquartile range (IQR). Significantly different if indicated as (*) for controls versus diabetes and (†) for D−Comps versus D+Comps.
