Increased Toll-Like Receptor 2 Expression in Peptidoglycan-Treated Blood Monocytes Is Associated with Insulin Resistance in Patients with Nondiabetic Rheumatoid Arthritis

Figure 5

Relationship between TNF-α concentration and TLR2 expression (calculated as percentage of CD14⁺ monocytes expressing TLR2) in monocytes after stimulation with 10 μg/mL of peptidoglycan in RA patients and normal controls (NC). (a) TLR2 expression significantly correlated with TNF-α concentration in RA patients (𝑟=0.484,𝑃=0.014); (b) no significant correlation in normal controls (𝑟=0.469,𝑃=0.172).

(a)

(b)