Mediators of Inflammation / 2012 / Article / Tab 2

Research Article

Interleukin-1β Accelerates the Onset of Stroke in Stroke-Prone Spontaneously Hypertensive Rats

Table 2

Effect of continuous IL-1β administration to SHR.

Before1 week2 weeks3 weeks4 weeks

BW (g)Control268.7 ± 9.5295.5 ± 10.4316.0 ± 11.7327.9 ± 10.4335.4 ± 10.7
IL-1β266.4 ± 8.8290.3 ± 11.2300.0 ± 10.1**317.9 ± 11.2326.8 ± 11.4
SBP (mmHg)Control173 ± 11158 ± 12181 ± 17173 ± 14181 ± 8
IL-1β175 ± 10161 ± 11172 ± 16171 ± 10174 ± 14
IL-1β (pg/mL)Control24.6 ± 15.526.1 ± 5.933.5 ± 17.737.9 ± 12.621.9 ± 8.2
IL-1β25.4 ± 19.265.4 ± 18.8***66.5 ± 20.6***61.2 ± 30.7*24.3 ± 6.2
Intake (g/day)Control23.9 ± 1.120.8 ± 1.120.6 ± 0.718.7 ± 0.9
IL-1β22.6 ± 1.1*19.7 ± 1.0*20.8 ± 0.919.0 ± 0.9

Data presented as mean ± SD. Body weight (BW), systolic blood pressure (SBP), and plasma level of IL-1β were measured at before (10 weeks of age) and every one week of IL-1β administration. Food intake (Intake) is presented as the mean weight of food eaten per day during each week. * , ** , *** versus Control by unpaired Student -test. in each group.