Mediators of Inflammation

Research Article

Interleukin-1β Accelerates the Onset of Stroke in Stroke-Prone Spontaneously Hypertensive Rats

Table 5

Magnitude and location of infarction, hemorrhage, or edema for individual rats in each group from Figure 4.
LocationInfarctionHemorrhageEdema
123456123456123456
Control                  
Rat #1−−++−−−−−+−−−−+++++++++−−
2−−−−−−−−−−−−−−−−−−
3++−+++++++−−++−+++++++−−+++++++++++−−
4−−−−−−−−−−−−−−−−−−
5−−−−−−−−−−−−+++−−−−
6−−−−−−−−−−−−−−−−−−
7−−−−−−−−+−−−−−−−−−
8++++++−++++−++++++−−−−+++++++++++−
9++++−−−−−+++−−−−++++++−−−−
10−−−−−−−−−−−−+++++−−−−
IL-1β                  
Rat #1+++−−−−+++−++−−+++−+−−
2−−−−−−−−++++−+−−−−−−
3−++−−−−−+−+−−+++++++−−
4−++++++−−−−++++++−−++++++++++−−
5−−−−−−−−−−−−−−−−−−
6++++−−−−−++−−−−−+++++−−−−
7−−++−−−−−−−−−−−−−−
8+−+++++++−−−++++++++−++++++++++−−
9+++++−+−−+++−−+−−+++++++−−
10−−+++−+++++−−−−−−−−−−+++++++++−
The brain was removed after death and fixed with 10% buffered formalin solution. Locations 1–6 indicate the section of stroke: 1 is frontal, 6 is rear. Increasing number of + indicates stronger changes, − indicates no abnormality. Rats were numbered in order of the onset of stroke; #1 was the first rat where stroke occurred in each group.