CXCR2 in Acute Lung Injury

Table 1

CXCR2 ligands in mice and humans.

Systematic name	Receptor	Mouse	Human
CXCL1	CXCR2	KC	GROα, MGSA
CXCL2	CXCR2	MIP-2	GROβ, MIP-2α
CXCL3	CXCR2	MIP-2	GROγ, MIP-2β
CXCL5	CXCR2	LIX	ENA-78
CXCL6	CXCR1,2	CKα-3	GCP-2
CXCL7	CXCR2	n/a	NAP-2
CXCL8	CXCR1,2	n/a	IL-8

CXCR1, 2 binding ligands modified from ref. [33]. GRO: growth-related oncogene; MGSA: melanoma growth stimulatory activity; KC: keratinocyte-derived chemokine; MIP: macrophage inflammatory protein; PF: platelet factor; ENA: epithelial cell-derived neutrophil-activating factor; LIX: lipopolisaccharide-induced CXC human chemokine; GCP: granulocyte chemotactic protein; CK: chemokine; NAP: neutrophil-activating protein; IL: interleukin.