Pegylated Arginine Deiminase Downregulates Colitis in Murine Models

<table>Effect of ADI-PEG on macrophage infiltration in colonic tissue from colitic IL-10-deficient mice. ADI-PEG markedly decreased submucosal macrophage infiltration and iNOS expression in DSS-induced colitic IL-10-deficient as well as WT mice (not shown). (<svg height="11.225" id="M65" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 36.237499 11.225" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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Mediators of Inflammation

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Figure 4

Figure 4: Pegylated Arginine Deiminase Downregulates Colitis in Murine Models 