Pegylated Arginine Deiminase Downregulates Colitis in Murine Models
Effect of ADI-PEG on macrophage infiltration in colonic tissue from colitic IL-10-deficient mice. ADI-PEG markedly decreased submucosal macrophage infiltration and iNOS expression in DSS-induced colitic IL-10-deficient as well as WT mice (not shown). (/group).
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